This was the second Messerschmitt design for a high-altitude single-seat fighter. It differed from the Me P.1110/I mainly in the V-tail unit and the annular air intake behind the cockpit. Like the Me P.1110/I, the Me P.1110/II had 40 degree swept-back wings, an HeS 011 jet engine and was armed with three MK 108 30mm cannon in the nose with a provision for two more in the wing roots.